From Health Canada:
This communication is to inform you of a surgical condition termed Intraoperative Floppy Iris Syndrome (IFIS)1 that has been observed during phacoemulsification cataract surgery in some patients currently or recently treated with alpha -1 blocker therapy. This variant of small pupil syndrome is characterised by the combination of a flaccid iris that billows in response to intraoperative irrigation currents, progressive intraoperative miosis despite preoperative dilation with standard mydriatic drugs, and potential prolapse of the iris toward the phacoemulsification incisions. ...more
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