Tuesday, March 04, 2008

Discovery could lead to 'tighter tummy' drug

From the Saskatoon Star Phoenix:
British scientists have discovered proteins that allow the gut to expand to make way for food, a finding that could lead to a drug for "tighter tummies" and a chemical alternative to stomach-shrinking surgery.

The human stomach can relax and expand to 25-times its normal "resting" volume, which explains why "we can pack in our Christmas dinner or our Thanksgiving dinner, or whatever festival we choose to think of," says Brian King, a senior lecturer in physiology at University College London.

King has identified receptors for proteins that relax the muscles of the gut. His team is testing different chemicals that would block these receptors and prevent the stomach from expanding, so that people would eat less and feel fuller, faster. ...more

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